The chart opens on Wegovy® injection and shows the schedule in Table 1 of its US label: four steps of 4 weeks, then the 2.4 mg maintenance dose from week 17. Choose "Wegovy® pill" to see the tablet's 30-day steps. These are the label's steps, quoted, and not a plan for anyone: the prescriber decides the dose, and may keep a person on a step for longer or lower it.
Ozempic®
Semaglutide injection, once a week, for adults with type 2 diabetes.
Step on the label
Optional step
Maintenance dose
Ozempic®: the label's dose steps
Dose
When the label allows it
On the label
0.25 mg once a week
Weeks 1 to 4
Starting dose
0.5 mg once a week
From week 5
Maintenance dose
1 mg once a week
After at least 4 weeks on 0.5 mg (week 9 at the earliest)
Maintenance dose, Optional
2 mg once a week
After at least 4 weeks on 1 mg (week 13 at the earliest)
Maintenance dose, Optional, Highest dose
The label allows 1 mg, and then 2 mg, when more glycemic control is needed, each after at least 4 weeks on the dose before.
The prescriber decides the dose, and may keep a person on a step for longer or lower it.
Wegovy®
Semaglutide injection, once a week. The steps shown are for weight reduction in adults.
Step on the label
Maintenance dose
Wegovy®: the label's dose steps
Dose
When the label allows it
On the label
0.25 mg once a week
Weeks 1 to 4
Starting dose
0.5 mg once a week
Weeks 5 to 8
1 mg once a week
Weeks 9 to 12
1.7 mg once a week
Weeks 13 to 16
Maintenance dose
2.4 mg once a week
From week 17
Maintenance dose
7.2 mg once a week
After at least 4 weeks on 2.4 mg
Optional, Highest dose
For weight reduction in adults, the label's maintenance dose is 1.7 mg or 2.4 mg (recommended). It allows 7.2 mg (Wegovy® HD) for people who have tolerated 2.4 mg for at least 4 weeks when more weight reduction is clinically indicated.
The EU product information differs on 7.2 mg: only for adults with a BMI of 30 or more at the start of treatment, back to 2.4 mg if 7.2 mg brings no further weight improvement, and possibly given as three 2.4 mg injections. (EU product information, § 4.2)
The prescriber decides the dose, and may keep a person on a step for longer or lower it.
Wegovy® pill
Semaglutide tablet, once a day, from the same US label as Wegovy® injection.
Step on the label
Maintenance dose
Wegovy® pill: the label's dose steps
Dose
When the label allows it
On the label
1.5 mg once a day
Days 1 to 30
Starting dose
4 mg once a day
Days 31 to 60
9 mg once a day
Days 61 to 90
25 mg once a day
From day 91
Maintenance dose, Highest dose
The label's maintenance dose is 25 mg once a day, reached in steps of 30 days.
How the label says to take it: one tablet in the morning on an empty stomach, with up to 4 fl oz (118 mL) of water and no other liquid, swallowed whole. Then wait at least 30 minutes before eating, drinking or taking other oral medicines. No more than one tablet a day.
The EU product information differs: it uses steps of at least 4 weeks instead of 30 days, a fast of at least 8 hours before the tablet, up to 120 mL of water, and the same 30-minute wait. (EU product information, § 4.2)
The prescriber decides the dose, and may keep a person on a step for longer or lower it.
Mounjaro®
Tirzepatide injection, once a week, for type 2 diabetes. The steps shown are for adults.
Step on the label
Optional step
Mounjaro®: the label's dose steps
Dose
When the label allows it
On the label
2.5 mg once a week
From week 1
Starting dose
5 mg once a week
After at least 4 weeks on 2.5 mg (week 5 at the earliest)
Optional
7.5 mg once a week
After at least 4 weeks on 5 mg (week 9 at the earliest)
Optional
10 mg once a week
After at least 4 weeks on 7.5 mg (week 13 at the earliest)
Optional
12.5 mg once a week
After at least 4 weeks on 10 mg (week 17 at the earliest)
Optional
15 mg once a week
After at least 4 weeks on 12.5 mg (week 21 at the earliest)
Optional, Highest dose
The label raises the dose in 2.5 mg steps, after at least 4 weeks on the current dose, when more glycemic control is needed. Its maximum for adults is 15 mg.
The EU product information differs: it raises 2.5 mg to 5 mg after 4 weeks and names 5 mg, 10 mg and 15 mg as the maintenance doses. (EU product information, § 4.2)
The prescriber decides the dose, and may keep a person on a step for longer or lower it.
Zepbound®: weight
Tirzepatide injection, once a week, for weight reduction and long-term maintenance.
Step on the label
Optional step
Maintenance dose
Zepbound®: weight: the label's dose steps
Dose
When the label allows it
On the label
2.5 mg once a week
Weeks 1 to 4
Starting dose
5 mg once a week
From week 5
Maintenance dose
7.5 mg once a week
After at least 4 weeks on 5 mg (week 9 at the earliest)
Optional
10 mg once a week
After at least 4 weeks on 7.5 mg (week 13 at the earliest)
Maintenance dose, Optional
12.5 mg once a week
After at least 4 weeks on 10 mg (week 17 at the earliest)
Optional
15 mg once a week
After at least 4 weeks on 12.5 mg (week 21 at the earliest)
Maintenance dose, Optional, Highest dose
The label calls 2.5 mg a starting dose that is not approved for maintenance. After 5 mg, it allows 2.5 mg steps, each after at least 4 weeks on the current dose. Its maintenance dose is 5 mg, 10 mg or 15 mg.
The prescriber decides the dose, and may keep a person on a step for longer or lower it.
Foundayo®
Orforglipron tablet, once a day.
Step on the label
Optional step
Foundayo®: the label's dose steps
Dose
When the label allows it
On the label
0.8 mg once a day
From day 1
Starting dose
2.5 mg once a day
After at least 30 days on 0.8 mg (day 31 at the earliest)
5.5 mg once a day
After at least 30 days on 2.5 mg (day 61 at the earliest)
9 mg once a day
After at least 30 days on 5.5 mg (day 91 at the earliest)
Optional
14.5 mg once a day
After at least 30 days on 9 mg (day 121 at the earliest)
Optional
17.2 mg once a day
After at least 30 days on 14.5 mg (day 151 at the earliest)
Optional, Highest dose
After 5.5 mg, the label allows 9 mg, 14.5 mg and 17.2 mg, each after at least 30 days on the current dose, based on treatment response and tolerability.
How the label says to take it: with or without food, swallowed whole, no more than one tablet a day. With a strong CYP3A4 inhibitor, the label's maximum is 9 mg.
Foundayo® is not yet authorised in the EU. The EMA's committee (CHMP) gave a positive opinion in October 2026. (EU product information)
The prescriber decides the dose, and may keep a person on a step for longer or lower it.
How does the Wegovy schedule step up?
The label's instruction is short: "Initiate at 0.25 mg once weekly for 4 weeks. Then follow the dosage escalation schedule in Table 1, titrating every 4 weeks to achieve the maintenance dosage." Table 1 applies to every approved use in adults and in children aged 12 and older:
How does the Wegovy schedule step up?
Weeks
Once-weekly dose
1 to 4
0.25 mg
5 to 8
0.5 mg
9 to 12
1 mg
13 to 16
1.7 mg
17 onward
2.4 mg
So the usual maintenance dose arrives after 16 weeks of lower doses. For weight reduction in adults, the label also allows 1.7 mg as the maintenance dose and calls 2.4 mg the recommended one. If a step is not tolerated, the label says to consider delaying the next one for 4 weeks.
Where does 7.2 mg fit?
Wegovy® HD is a 7.2 mg single-dose pen, added to the same US label in March 2026. The label allows it for weight reduction in adults only: "For patients who tolerate the 2.4 mg dosage for at least 4 weeks and additional weight reduction is clinically indicated, the dosage may be increased to a maximum dosage of 7.2 mg subcutaneously once weekly."
The chart draws 7.2 mg as the highest dose rather than as a step at a set week, because the label ties it to time on 2.4 mg and to a clinical decision, not to the calendar. Its safety and effectiveness are not established in children.
The EU product information is stricter on 7.2 mg. It is for adults with a BMI of 30 or more at the start of treatment, the dose goes back to 2.4 mg if 7.2 mg brings no further improvement in body weight, and it can be given as one 7.2 mg injection or three 2.4 mg injections, depending on the device.
How does the Wegovy pill schedule work?
The tablets are on the same US label, in Table 2, and they step every 30 days instead of every 4 weeks:
How does the Wegovy pill schedule work?
Days
Once-daily dose
1 to 30
1.5 mg
31 to 60
4 mg
61 to 90
9 mg
91 onward
25 mg
The label's maintenance dose is 25 mg once daily, and it has intake rules: one tablet in the morning on an empty stomach, with up to 4 fl oz (118 mL) of plain water, swallowed whole, then a wait of at least 30 minutes before food, drinks or other oral medicines. The EU product information counts the steps as at least 4 weeks each, asks for a fast of at least 8 hours before the tablet and allows up to 120 mL of water.
What can this chart not tell you?
When your own steps happen. The weeks in the table are the label's earliest. A prescriber can hold a step longer when a dose is not well tolerated.
Whether 7.2 mg applies. That depends on tolerating 2.4 mg and on a clinical judgment, both outside a chart.
How to move between the pill and the injection. The label has its own rules for that, and the prescriber applies them.
Frequently asked questions
When does Wegovy reach 2.4 mg?
At week 17 on the label's schedule, after four 4-week steps of 0.25, 0.5, 1 and 1.7 mg.
Is 7.2 mg the new standard Wegovy dose?
No. The label still calls 2.4 mg the usual recommended maintenance dose. 7.2 mg is its maximum, allowed after at least 4 weeks on 2.4 mg when more weight reduction is clinically indicated.
How long does the Wegovy pill take to reach 25 mg?
90 days of lower doses: 1.5, 4 and 9 mg for 30 days each. The 25 mg dose starts on day 91.